Leishmaniasis (by sandlfies) update ?
#1
Forum Regular
Thread Starter
Joined: Oct 2013
Posts: 178
Leishmaniasis (by sandlfies) update ?
hi
anyone knows if vets in Spain are starting to provide the vaccine ?
seems it's now tested and effective;
http://www.fda.gov/BiologicsBloodVac.../ucm342667.htm
also what do you for yourselves against those sandflies during the dangerous months ?
thanks
''The study’s finding that an experimental vaccine triggers a stronger immune response in dogs than the commercial one is important because dogs are a major source of human infections in tropical areas. Dogs also occasionally spread the disease in Northern Europe, the United States, and Canada. Drug treatment usually fails to cure infections in dogs and remaining parasites tend to grow resistant to drug treatment. Dogs can then pass on these drug-resistant parasites to humans.
The FDA scientists compared the immunogenicity (ability to trigger immune responses) of the commercial vaccine (Leishmune®) in dogs with that of an experimental vaccine made from genetically modified and weakened live L. donovani parasites that lacked a critical gene called LdCen. Parasites lacking this gene (i.e., LdCen-/- parasites), cannot grow and reproduce inside the macrophage, and eventually die.
Dogs vaccinated with the LdCen-/- parasites had a stronger immune response than those receiving the commercial vaccine. Specifically, their immune system produced more anti bodies and immune system cells called lymphocytes. There was also increased production of certain key chemical signals released by lymphocytes that help stimulate the immune response.
Overall, the findings of FDA scientists demonstrated the potential of the LdCen-/- parasite as a canine vaccine against visceral leishmaniasis and suggest that it is a good candidate for further evaluation to demonstrate its safety and effectiveness.''
anyone knows if vets in Spain are starting to provide the vaccine ?
seems it's now tested and effective;
http://www.fda.gov/BiologicsBloodVac.../ucm342667.htm
also what do you for yourselves against those sandflies during the dangerous months ?
thanks
''The study’s finding that an experimental vaccine triggers a stronger immune response in dogs than the commercial one is important because dogs are a major source of human infections in tropical areas. Dogs also occasionally spread the disease in Northern Europe, the United States, and Canada. Drug treatment usually fails to cure infections in dogs and remaining parasites tend to grow resistant to drug treatment. Dogs can then pass on these drug-resistant parasites to humans.
The FDA scientists compared the immunogenicity (ability to trigger immune responses) of the commercial vaccine (Leishmune®) in dogs with that of an experimental vaccine made from genetically modified and weakened live L. donovani parasites that lacked a critical gene called LdCen. Parasites lacking this gene (i.e., LdCen-/- parasites), cannot grow and reproduce inside the macrophage, and eventually die.
Dogs vaccinated with the LdCen-/- parasites had a stronger immune response than those receiving the commercial vaccine. Specifically, their immune system produced more anti bodies and immune system cells called lymphocytes. There was also increased production of certain key chemical signals released by lymphocytes that help stimulate the immune response.
Overall, the findings of FDA scientists demonstrated the potential of the LdCen-/- parasite as a canine vaccine against visceral leishmaniasis and suggest that it is a good candidate for further evaluation to demonstrate its safety and effectiveness.''
#2
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Joined: May 2008
Posts: 1,878
Re: Leishmaniasis (by sandlfies) update ?
I replied to your other post, will add this here, at least one vet in the Chiclana area does the injections, a friends dogs had them last year and their boosters this year.
#3
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Joined: Oct 2013
Posts: 178
Re: Leishmaniasis (by sandlfies) update ?
hi
then he must be using the 2013 vaccine, which implies several dosages then once a year booster indeed.
that one ?
http://www.virbac.ch/fr/kleintier/ca...d-us.-vet.html
not the Brazilian one I suppose then.
http://www.leishmune.com.br/
then he must be using the 2013 vaccine, which implies several dosages then once a year booster indeed.
that one ?
http://www.virbac.ch/fr/kleintier/ca...d-us.-vet.html
not the Brazilian one I suppose then.
http://www.leishmune.com.br/
#4
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Posts: 1,878
Re: Leishmaniasis (by sandlfies) update ?
As far as I can remember yes, initially 3 injections spread over time then this year the booster. I have not read up on it, my dog has border line brown tick disease counts, negative for Leishmaniasis.
#5
Just Joined
Joined: Oct 2013
Posts: 28
Re: Leishmaniasis (by sandlfies) update ?
the leishmaniasis is incurably.
#6
Re: Leishmaniasis (by sandlfies) update ?
Our vets are heavily advertising the availability in the surgery so I would have thought it would be available at all vets now.
#7
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Location: Los Martinez
Posts: 858
Re: Leishmaniasis (by sandlfies) update ?
I'm going to point our friends at this post. Sadly their 7 month old pup had this about 2 months back and its costing them an arm and leg in vets bills for treatment!
#8
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Location: Beckenham, London borough Bromley
Posts: 1,617
Re: Leishmaniasis (by sandlfies) update ?
Hola
There are apparently two types of Leishmaniasis - one of which can be arrested allowing the dog to live.
But the real point is that prevention is better than cure, so I had my dogs inoculated; three jabs the first year after a blood test, then an annual booster. One further point, the Leishmaniasis jab cannot be given at the same time as the other yearly jabs - there must be at least three weeks between them.
Davexf
There are apparently two types of Leishmaniasis - one of which can be arrested allowing the dog to live.
But the real point is that prevention is better than cure, so I had my dogs inoculated; three jabs the first year after a blood test, then an annual booster. One further point, the Leishmaniasis jab cannot be given at the same time as the other yearly jabs - there must be at least three weeks between them.
Davexf