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-   -   Paracetamol vs Tylenol- Both The Same? (https://britishexpats.com/forum/trailer-park-96/paracetamol-vs-tylenol-both-same-884411/)

petitefrancaise Oct 10th 2016 5:36 am

Re: Paracetamol vs Tylenol- Both The Same?
 

Originally Posted by brit_usa2014 (Post 12072366)
Are Paracetamol & Tylenol both the same? Google says yes (it contains the same active ingredients) but I find paracetamol much better for giving pain reliefs.

Any insights?

the "other ingredients" have some differences. This may affect how they work, I'm trying to remember a past discussion on dental forum but I think we came down to this being a reason why some people "prefer" one to the other in spite of the active ingredients being the same.

Paracetamol =
Maize Starch
Pregelatinised Maize Starch
Stearic Acid

Tylenol=
magnesium stearate, modified starch, powdered cellulose, pregelatinized starch, sodium starch glycolate.


Codeine (solpadeine) in the UK really ought to be Rx only, it is addictive. In France it is Rx only.

mrken30 Oct 10th 2016 5:41 am

Re: Paracetamol vs Tylenol- Both The Same?
 
I think Codeine is pharmacist controlled in the UK, ie a Pharmacist has to authorize the sale from what I remember. Kaolin and Morphine has the same restrictions.

MidAtlantic Oct 10th 2016 5:43 am

Re: Paracetamol vs Tylenol- Both The Same?
 

Originally Posted by mrken30 (Post 12072933)
I think Codeine is pharmacist controlled in the UK, ie a Pharmacist has to authorize the sale from what I remember. Kaolin and Morphine has the same restrictions.

"Control" is a bit strong. As I recall, they ask a couple of simple questions then sell it to you.

petitefrancaise Oct 10th 2016 5:45 am

Re: Paracetamol vs Tylenol- Both The Same?
 

Originally Posted by MidAtlantic (Post 12072935)
"Control" is a bit strong. As I recall, they ask a couple of simple questions then sell it to you.

quite. It's a "cover your arse" exercise only by the pharmacists as far as I can see.

MidAtlantic Oct 10th 2016 5:49 am

Re: Paracetamol vs Tylenol- Both The Same?
 

Originally Posted by Rete (Post 12072896)
My sister has actually done this to me on several occasions without my knowing it. I would say I had a terrible headache or my shoulder hurt where the rod is set into the joint and she would give me Advil without my knowing it. Didn't work at all. I would go home and take my IB and be pain free within a half hour. Visit with the sis again and again she slips me the Advil and again it doesn't work but at home later the IB does. After the third time this happens, I ask what are you giving me? Advil the little minx replies. So I started carrying a small bottle of IB with me at all times. :ohmy: Since IB comes in so many different "shapes" from oval to small round pills and also gel caps, I didn't question that the shape was different. Anywho, I take what works for me. Having a rod in your upper arm from shoulder to elbow cup does mean pain on many occasions, thus I carry my relief with me now.

Interesting! I recall there being questions about some generics not working as well as the branded drug and the possible explanation being about the rate/level of absorption into the blood. Maybe that's the issue here also.

scrubbedexpat091 Oct 10th 2016 7:20 am

Re: Paracetamol vs Tylenol- Both The Same?
 
This med is the number one cause of acute liver failure in the US due to unintentional overdose.

yellowroom Oct 10th 2016 7:25 am

Re: Paracetamol vs Tylenol- Both The Same?
 
To get a generic license, the generic manufacturer has to show bioequivalence, ie their tablet releases the drug and the body absorbs at the same rate as the branded original. So in theory, they should perform the same. Many people do report a difference compared to the branded form - I would encourage people to dial the numbers on the back of the packets to report that if it doesn't work for you.

Ibuprofen gets more complicated because there are different salts/forms which do dissolve and absorb at different rates, such as ibuprofen lysine, arginate or sodium. The ibuprofen part is exactly the same, but is chemically "paired" with an inert atom or molecule that affects how fast the body takes it up. So there can be a demonstrable difference between the cheap, plain ibuprofen and the fancier branded "quick acting" forms.

yellowroom Oct 10th 2016 7:32 am

Re: Paracetamol vs Tylenol- Both The Same?
 

Originally Posted by mrken30 (Post 12072933)
I think Codeine is pharmacist controlled in the UK, ie a Pharmacist has to authorize the sale from what I remember. Kaolin and Morphine has the same restrictions.

good luck finding k&m in a British pharmacy these days. It's great for dodgy tummies, I find it very comforting. But considering the ingredients (not just the tiny amount of morphine - it also contains ethanol & chloroform) it's not really surprising.

AdobePinon Oct 10th 2016 8:06 am

Re: Paracetamol vs Tylenol- Both The Same?
 

Originally Posted by Jsmth321 (Post 12073010)
This med is the number one cause of acute liver failure in the US due to unintentional overdose.

Most likely when combined with alcohol. One pill can kill a "functioning alcoholic ".

Pulaski Oct 10th 2016 8:07 am

Re: Paracetamol vs Tylenol- Both The Same?
 

Originally Posted by yellowroom (Post 12073015)
To get a generic license, the generic manufacturer has to show bioequivalence, ie their tablet releases the drug and the body absorbs at the same rate as the branded original. So in theory, they should perform the same. Many people do report a difference compared to the branded form - I would encourage people to dial the numbers on the back of the packets to report that if it doesn't work for you. .....

Curiously though, and contrary to what you are implying, Rete's problem appears to be with the leading brand of ibuprofen, not a cheaper generic.

MidAtlantic Oct 10th 2016 8:20 am

Re: Paracetamol vs Tylenol- Both The Same?
 

Originally Posted by Pulaski (Post 12073041)
Curiously though, and contrary to what you are implying, Rete's problem appears to be with the leading brand of ibuprofen, not a cheaper generic.

The point is that, contrary to expectations, there is a difference between the effects of some branded and generic drugs. That is not to say the branded is always better, although that is what we tend to assume. In Rete's case it seems that the generic works better for her than the branded.

Sheepdip Oct 10th 2016 8:29 am

Re: Paracetamol vs Tylenol- Both The Same?
 

Originally Posted by mrken30 (Post 12072933)
I think Codeine is pharmacist controlled in the UK, ie a Pharmacist has to authorize the sale from what I remember. Kaolin and Morphine has the same restrictions.

Same with Voltarol - used to be my life saver and is now pharmacist controlled (after prescription only when I first had it) in the UK but prescription only here

Mallory Oct 10th 2016 10:47 am

Re: Paracetamol vs Tylenol- Both The Same?
 

Originally Posted by Pulaski (Post 12072665)
If you following the dose instructions there is zero harm. If you take 20 it will kill you.

There has been a history of young girls breaking up with their bf and taking an overdose as a drama queen, attention-seeking, behaviour. They have no plan to kill themselves, just pretend like they are. Unfortunately, they have no idea how dangerous even a small overdose of acetaminophen is. There is a history of many accidental deaths in this way. This is one of the reasons they sell them in small quantities in some countries.

Many mothers were buying acetaminophen because they thought it was safer than aspirin or NSAIDS for kids, not knowing of the above danger.

Pulaski Oct 10th 2016 11:38 am

Re: Paracetamol vs Tylenol- Both The Same?
 

Originally Posted by Mallory (Post 12073159)
There has been a history of young girls breaking up with their bf and taking an overdose as a drama queen, attention-seeking, behaviour. They have no plan to kill themselves, just pretend like they are. Unfortunately, they have no idea how dangerous even a small overdose of acetaminophen is. .....

Yup, 2-3 days of excruciating pain while your liver rots, leading inexorably to death. :(

yellowroom Oct 10th 2016 12:36 pm

Re: Paracetamol vs Tylenol- Both The Same?
 

Originally Posted by Pulaski (Post 12073041)
Curiously though, and contrary to what you are implying, Rete's problem appears to be with the leading brand of ibuprofen, not a cheaper generic.

i left it deliberately vague. Some people report one version works for them and the other doesn't. I'd encourage people to report the ones that don't work for them. Not because of any sinister reasons but because manufacturers are obligated to keep records of numbers of "adverse events" and it may help long term to work out why there is a difference.


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